Biology Project Abstract
CATCHING DEPRESSION FROM YOUR BEST FRIEND? THE CORRELATION BETWEEN THE BORNA VIRUS AND CLINICAL DEPRESSION
Presenters:
Kate Moss, Illinois Mathematics and Science Academy, 1500 West Sullivan Road, Aurora, IL, 60506; katybug@imsa.edu
Whitney Rossmiller, Illinois Mathematics and Science Academy, 1500 West Sullivan Road, Aurora, IL, 60506; whitraye@imsa.edu
Advisors:
Dr. David Evenson, Illinois Mathematics and Science Academy, 1500 Sullivan Road, Residential Life, Aurora, IL,60506, 630-907-5988; evenson@imsa.edu
Dr. Edwin Goebel, Illinois Mathematics and Science Academy, 1500 Sullivan Road, Biology, Aurora, IL, 60506; 630-907-5090; goebel@imsa.edu
Abstract:
Studies have shown a correlation of infection by the Borna Disease Virus (BDV) with the development of clinical depression. Our inquiry undertook an investigation of the literature in order to understand the research and analyze the conclusions. Several studies tested patients with depression to determine whether they carry antibodies or the RNA of this virus. When compared to healthy, non-depressed controls, the results showed a significant correlation of antibody presence and depression. The standard for determining whether an infectious agent causes disease is whether Koch's postulates are met. Healthy rabbits were transfused with blood from infected patients and observed for signs of depression. The rabbits exhibited signs of depression such as sluggishness and loss of appetite. After reviewing the literature, we believe that infection with the Borna Virus increases the risk of clinical depression.